David Mobley, Ph.D.

Vice Chair, Professor; University of California, Irvine

Portrait of David Mobley

David Mobley, Ph.D., is a vice chair and professor at the University of California, Irvine, where his research focuses on predicting thermodynamic properties from molecular simulations with an emphasis on problems relating to pharmaceutical drug discovery. These include transfer free energies, protein-ligand docking, binding free energy simulations and small molecule solubility prediction. Methods recently developed and applied have achieved far greater accuracies at computing and predicting binding affinities as compared with previous methods, which are being applied on pharmaceutically relevant proteins. His work focuses on using so-called alchemical free energy techniques for predicting binding affinities using molecular simulations.

Dr. Mobley’s honors and awards include National Science Foundation CAREER award and the Hewlett-Packard Outstanding Junior Faculty Award from the American Chemical Society.

Dr. Mobley earned a bachelor of science degree in physics, a master of science degree in physics, and a doctor of philosophy degree in physics from the University of California, Davis. He was a postdoctoral fellow at University of California in San Francisco.

Open Science Contributions

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