Job Title: Senior Research Associate/Scientist, Biophysics and Structural Biology (Boston Seaport)
We are currently seeking a Senior Research Associate/Scientist I in Biophysics and Structural Biology to work onsite with our agile team in our Boston Seaport office/lab. Please apply to the role via our careers page: https://psivant.com/company/careers/
About Psivant Therapeutics
Psivant Therapeutics is creating better therapeutics through an integrated molecular design paradigm that leverages best-in-class physics-based + AI technologies arising from decades of research and innovation. Our focus is first-in-class inflammation and immunology (I&I) small molecule therapeutics. We have assembled a diverse team with extensive experience across research disciplines ranging from physics and computer science to chemistry, biology, biochemistry, and structural biology. This continuum of complementary skills is essential for driving our scientific vision and bringing meaningful therapeutics to patients in need. We are patient-inspired, perseverant, synergistic, supportive, intrepid, and inclusive. If you are inspired to bring better medicines to patients within a collaborative organization that combines advanced computation with drug discovery, then Psivant could be the right place for you.
Here at Psivant – we are a lean, high performing team. We want individuals who are both smart and collaborative– who want to get things done. We push boundaries for growth in both ourselves and our science. We look for people who thrive in high-paced, nimble, early-stage biotech environments.
Read More about Us
Primary Responsibilities
- Perform biochemical and biophysical assays to characterize small molecule interactions with TNF super family members
- Assays include surface plasmon resonance (SPR), differential scanning fluorimetry (DSF), fluorescence polarization (FP), fluorescence resonance energy transfer (FRET), and AlphaLISA
- Analyze and interpret data
- Maintain detailed electronic notebook, develop protocols, summarize results
- Upload data to internal database
- Contribute to laboratory organization and maintenance
- Present results to the project team and leadership
Qualifications
- BS/MS in Biology, Biochemistry, Chemical Biology, or Biophysics with at least 2-3 years of drug discovery experience or Ph.D. with 1-2 years of drug discovery experience
- Experience with assays such as FRET, FP, MST, SPR, DSF, or ITC
- Experience with protein expression, purification from bacterial, insect and/or mammalian systems
- Experience with automation such as Tecan, Echo, Mosquito, Integra Assist, Formulatrix suite or Bravo
- Proven ability to work independently, troubleshoot, and interpret data
- Attentive to detail, organized, good communicator
- Eager to learn and contribute in a fast-paced environment
Psivant Therapeutics provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.